Explore Our
  Research Projects

"What are the
  biochemical
   mediators of
    cavitation in
     tuberculosis?"

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"FDA approved
  TNF-response
   inhibitor, Tofacitinib,
    is an effective
     host-directed therapy
      in a mouse model
       of tuberculosis."

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"A BCG
  delivered
   STING agonist
    is a better
     TB vaccine
      than BCG-WT"

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"Treg-depletion
  with a diphtheria
   toxin fusion
    protein (Ontak)
     is beneficial
      in a mouse model."

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"M. tb secretes
  a STING agonist,
   c-di-AMP, which
    triggers autophagy
     and increased
      Type I IFN responses"

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"Does host
  enzyme PARP-1
   contribute to
    tuberculosis
     pathogenesis?"

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~ The Bishai Laboratory ~
The Johns Hopkins University School of Medicine
The Department of Medicine, Division of Infectious Diseases

The Bishai Laboratory is a Member of the Center for Tuberculosis Research


1550 Orleans Street, Bldg. CRBII, Room 108
Baltimore, MD 21231-1001
Tel: 410-955-3507
Fax: 410-614-8173
E-mail: wbishai1@jhmi.edu

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